苏州Sea Run Holding授权代理商,正品 Sea Run Holding鲑鱼纤维蛋白原

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Thermofisher旗下Gibco培养系列、ABI细胞计数仪PCRInvitrogen分子生物学试剂Qubit3.0AmbionRNA相关试剂Molecular probes试剂、Pierce蛋白相关试剂盒Nanodrop One/OneCParafilm封口膜;Viskase透析袋;Sigma-Aldrich试剂;AccuStandard 标准品Millipore抗体Glen Research 核酸合成试剂Bio-Rad电泳仪PCRNanocsPEG聚合物;  Chromotek羊驼抗体   Polysciences转染试剂  Echelon-inc 脂类研究试剂盒   R&D Systems抗体及Elisa试剂盒 Jackson二抗及封闭血清 Biotium 荧光染料;NEB内切酶及NGS相关产品;  Athens Research & Technology人类蛋白及抗血清;  Illumina二代测试试剂盒 Tocris 小分子试剂 TwistDx恒温扩增试剂盒(RPA Enzymatics二代测序酶Novus抗体及Elisa试剂盒AG scientific潮霉素B、放线菌酮、G-418Plantmedia植物培养系列及抗体;Agilent 2100生物分析仪;Biolog耗材BiomatikElisa试剂盒Covaris基因打断仪;CST抗体DharmaconsiRNA产品。


据悉,Pfenex Inc.于美国纽约证券交易所上市,为高科技生物研发公司,拥有重组DNA蛋白质制造平台(Pfenex Expression Technology®)专利,能有效地生产生物依制遴选药品、同等疗效遴选产品以及遴选疫苗。Pfenex的主导遴选药品为PF708,一种Forteo® (特立帕肽)的等效药品,用于治疗骨质疏松,而其新型炭疽疫苗遴选药品Px563L及RPA563则透过优先开发合同而得到美国政府提供资金。此外,Pfenex正与Jazz Pharmaceuticals合作开发血液╱肿瘤产品,其中包括PF743(一种重组天冬酰胺酶)及PF745(一种具有半衰期延长技术的重组天冬酰胺酶)。此外,Pfenex还生产包括Lucentis®及Neulasta®在内的生物类似遴选药品。


                       
美国Pfenex公司总部在加利福尼亚的圣迭戈,是一家为生物制药和疫苗开发机构提供临床前cGMP级蛋白质的全球领先供应商。利用公司的核心技术——Pfēnex Expression Technology™在重组蛋白表达方面的应用,使Pfenex能够快速开发和生产高质量的蛋白和蛋白试剂。现Pfenex公司通过旗下的Reagent Proteins分部为全球药物研究和开发机构生产并销售相关蛋白产品。Pfēnex Expression Technology™核心专利技术结合了一个自动启用高通量平行菌株筛选技术,提供前所未有的能快速成功识别表达高可溶性滴度和活性蛋白的菌株。Pfenex公司已正式授权上海权阳贸易有限公司为中国地区首家且独家产品代理经销商。

Salmon thrombin (三文鱼凝血酶/鲑鱼凝血酶)

 

Catalog Number

SEA-135

 

Description

Plasma protein from the blood of farmed S. salar

 

Product Background

Background: 
- Fibrin gels made from salmon proteins have demonstrated remarkable properties in neuron survival and growth. 
- Salmon fibrin gels represent the optimal matrix for neuronal cell cultural
- Salmon fibrin gels have also properties superior to mammalian gels in an in vitro angiogenesis model. The salmon gels were 60-188% more efficient than human fibrin gels supporting growth of human endothetlial cells. These results indicate that salmon fibrin may be attractive alternate ECM for support of microvascular network formation. 
- Salmon fibrinogen and thrombin can be used at room temperature 
- Soft salmon fibrin gels have been shown to promote selection and growth of tumorigenic cells

Research Targets:
- Regenerative Medicine  
- Spinal Cord Injury 
- Neural cell regrowth 
- Pain & CNS Investigators 
- Stem Cell Research 
- Cancer stem cell research

Benefits: 
- Superior Performance- demonstrated superiority to Matrigel as an extracellular matrix for neuronal cell growth.
- Safety from mammalian pathogens 
- Easy of rehydration & improved thermal properties.

For more information on Salmon fibrinogen and thrombin: 
Sieminski and Gooch. 2004. J Biomater Sci Polym. Ed 15(2):237-42
Ju, et al. Biomaterials. 2007 April; 28 (12): 2097-2108 
Liu J, et al. Nat Mater. 2012 Jul 1;11(8):734-41. doi: 10.1038/nmat3361.
Information Sheet 
Application Note 

 

Category

Miscellaneous Proteins

 

 

Formulation

Dialyzed in 200 mM Tris, 3 mM CaCl2, 0.15M NaCl, pH 7.2-7.5.
 

 

Reconstitution

Rehydrate with H2O at room temperature or below. Remove the amount to be used that day, and hold on ice. Salmon thrombin retains greater than 80% activity after 24 hours on ice. Aliquot remaining thrombin and freeze at <-60°C 

 

Storage

Freezer (<-10°C). Avoid freeze-thaw cycles

 

Purity

Affinity chromatography on immobilized heparin, SDS-PAGE

Sourced from salmon shown by certified tests to be negative for fish viruses. Activity tested by spectrophometric analysis of peptide hydrolysis (Chromozyme), and compared to human standard.
Filtered to 0.2 u 

 

Activity

≥ 1000 Units/ mg protein

 

References

US Patent #6,007,811 and 6,861,225. Michaud et al, 2002. Thrombosis Research 107:245-54 

Sieminski and Gooch. 2004. J Biomater Sci Polym. Ed 15(2):237-42

Ju, et al. Biomaterials. 2007 April; 28 (12): 2097-2108 

Salmon fibrin treatment of spinal cord injury promotes functional recovery and density of serotonergic innervation

Liu J, et al. Nat Mater. 2012 Jul 1;11(8):734-41. doi: 10.1038/nmat3361.
 

Reagent Proteins is the Source for proteins. 
From custom protein production to our over 5,000 catalog proteins, we are a leading supplier of reagent, pre-clinical and cGMP grade proteins to the biopharmaceutical and vaccine development community. We ensure the cost-effective and rapid delivery of high quality recombinant proteins to enable your research and development efforts.

 



苏州蚂蚁淘生物科技有限公司是美国Xenotech公司和美国Pfenex公司在中国的授权代理经销商。 XenoTech公司是一家为全球药物公司、化学公司和研究机构提供符合GLP标准规范的体外药物代谢和药物间相互作用评价产品的公司,已成为全球多家制药公司非常信赖的合作伙伴和咨询专家。主要产品包含了体外药物代谢研究中涉及的各种人和动物肝细胞、微粒体、S9组分、细胞胞液等,还包含CYP450基因重组酶等相关产品。各类产品和服务方面所公布的信息均是美国官方FDA推荐的,可以预测药物安全、药效方面的个体差异和解释药物的副作用。

PfenexX,蚂蚁淘专业代理英国各大品牌,在线下单,万余种高质量抗体,价格短,货期短,全国代理,品牌保证,价格优惠,请详询有礼,苏州蚂蚁淘生物专业代理英国Sea Run HoldingX,正品保证 , 价格优惠.欢迎来询


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