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Pfenex/CRM197 - CRM197/1mg/525

CatalogNumberCRM-197DescriptionCRM197diphtheriatoxinmutant,recombinant.Pre-clinicalgrade.ProductBackgroundCRM197isanon-toxicmutantofdiphtheriatoxin1,2havingasingleaminoacidsubstitutionofglutamicacidforglycine.CRM197isawell-definedproteinandfunctionsasacarrierforpolysaccharidesandhaptensmakingthemimmunogenic.Itisutilizedasacarrierproteininanumberofapprovedconjugatevaccinesfordiseasessuchasmeningitisandpneumococcalbacterialinfections.PfenexCRM197isarecombinantformexpressedinPseudomonasfluorescensusingthePfenexExpressionTechnologyTMplatform.Thisproductisavailableinbothpre-clinicalandcGMPgrade.FormoreinformationonCRM197orourothervaccinecarriers,pleasecontactusorvisitourknowledgecenterforarticles,publicationsandotherresourcesonCRM197andourothervaccinecarriers.SourcePseudomonasfluorescensSpeciesCoryNEBacteriumdiphtheriaeStorageStoreat2-8°CuponreceiptPurity Purity:>95%CRM197bySDS-PAGEAandBchaincontent<5%oftotalCRM197Endotoxin:<100EU/mgofproteinbyLALmethodDimer:<5%Uses Beforeuse,asepticallyreconstitutelyophilizedCRM197withsteriledeionizedwatertoaconcentrationof4mg/mLCRM197.ReconstitutedCRM197shouldbestoredat2-8°C.
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