企业QQ
官方微信
SelectiveinhibitorofclassIIahistonedeacetylases(HDACs).Exhibitstissue-selectiveinhibitionbetweenmembersofclassIIdeacetylasesinvivo;inhibitsHDAC4andHDAC5inskeletalmuscleandtheheartwithoutaffectingHDAC3activity.ArrestsmyogenesisthroughthestABIlizationofmyocyteenhancerfactor2D(MEF2D)-HDAC3/4complex.DisplaysnoinhibitionofclassIHDACactivityorexpression.
MC1568isalsoofferedaspartoftheTocriscreenEpigeneticsToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 314.31 |
| Formula | C17H15FN2O3 |
| Storage | Storeat+4°C |
| Purity | ≥96%(HPLC) |
| CASNumber | 852475-26-4 |
| PubChemID | 11381449 |
| InChIKey | QRDAPCMJAOQZSU-KQQUZDAGSA-N |
| Smiles | CN1C=C(/C=C/C(C2=CC(F)=CC=C2)=O)C=C1/C=C/C(NO)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 31.43 | 100 |
Thefollowingdataisbasedontheproductmolecularweight314.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.18mL | 15.91mL | 31.82mL |
| 5mM | 0.64mL | 3.18mL | 6.36mL |
| 10mM | 0.32mL | 1.59mL | 3.18mL |
| 50mM | 0.06mL | 0.32mL | 0.64mL |
SouthernBiotech/Goat Anti-Human Lambda-Alexa Fluor® 555/2070-32/1.0 mg
vectorlabs/Biotinylated Aleuria Aurantia Lectin (AAL)/B-1395/1 mg
vectorlabs/VECTASTAIN® Elite® ABC-HRP Kit (Peroxidase, Mouse IgG)/PK-6102/1 kit
vectorlabs/VECTASTAIN® Elite® ABC-HRP Kit (Peroxidase, Universal)/PK-6200/1 kit
vectorlabs/Unconjugated Musa Paradisiaca (Banana) Lectin (BanLec)/L-1410/5 mg
GiottoBiotech/Calmodulin N60D/5 mg/G02CLM60cn