产品资料

Tocris/Neuropeptide S (Mouse)/5857/1/1 mg

Description: Potent endogenous neuropeptide S receptor (NPSR) agonist

Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity

Potent endogenous neuropeptide S receptor (NPSR) agonist (EC₅₀ = 3 nM). Induces mobilization of intracellular Ca²⁺. Increases locomotor activity and wakefulness in mice. Also reduces anxiety-like behavior in mice.

Technical Data

M. Wt	2182.47
Formula	C₉₃H₁₅₆N₃₄O₂₇
Sequence	SFRNGVGSGAKKTSFRRAKQ
Storage	Store at -20°C
CAS Number	412938-74-0
PubChem ID	54581309
InChI Key	XBNIXBCJICZFRR-GYDKITGDSA-N
Smiles	[H]N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solubility	Soluble to 2 mg/ml in water

Solubility

Soluble to 2 mg/ml in water

Preparing Stock Solutions

The following data is based on the product molecular weight 2182.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	0.46 mL	2.29 mL	4.58 mL
5 mM	0.09 mL	0.46 mL	0.92 mL
10 mM	0.05 mL	0.23 mL	0.46 mL
50 mM	0.01 mL	0.05 mL	0.09 mL

Product Datasheets

Certificate of Analysis / Product Datasheet

Safety Datasheet

References

References are publications that support the products' biological activity.

Xu et al (2004) Neuropeptide S: a neuropeptide promoting arousal and anxiolytic-like effects. Neuron 43 487 PMID: 15312648

Keywords: Neuropeptide S (Mouse), supplier, Endogenous, neuropeptide, S, receptor, NPSR, agonists, agonism, wakefulness, arousal, anxiety, potent, anxiolytic, Other, Peptide, Receptors, Other, Peptide, Receptors, Tocris Bioscience

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