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Adipogen/GDC0032/SYN1202M001/1 mg
MoreInformation
ProductDetails
SynonymsGDC0032
ProductTypeChemical
Properties
FormulaC24H28N8O2
MW460.5
CAS1282512-48-4
PurityChemicals≥95%
AppearanceSolid.
SolubilitySlightlysoluble(<1mg l)="" in="" dmso="" or="" ethanol.="">
DeclarationManufacturedbySynKinase.
OtherProductDataTarget:PI3K|KinaseGroup:LipidKinases|Substrate:Lipid

ClickhereforOriginalManufacturerProductDatasheet
Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet.
InChiKeyBEUQXVWXFDOSAQ-UHFFFAOYSA-N
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
Use/StabilityStableforatleast2yearsafterreceiptwhenstoredat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
GDC-0032isapotent,next-generationβisoform-sparingPI3KinhibitortargetingPI3Kα/δ/γwithKiof0.29nM/0.12nM/0.97nM,>10foldselectiveoverPI3Kβ.
ProductReferences
  1. Discoveryof2-{3-[2-(1-isopropyl-3-methyl-1H-1,2-4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl]-1H-pyrazol-1-yl}-2-methylpropanamide(GDC-0032):aβ-sparingphosphoinositide3-kinaseinhibitorwithhighunboundexposureandrobustinvivoantitumoractivity:C.O.Ndubaku,etal.;J.Med.Chem.56,4597(2013)

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