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LKT/CX6258/C9200/25 mg
ProductIDC9200
CasNo.1202916-90-2
Purity≥98%
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

CX-6258isaninhibitorofPimkinasethatexhibitsanticancerchemotherapeuticactivity.Thiscompounddecreasestumorgrowthinanimalmodelsofcancer.

ProductInfo

CasNo.

1202916-90-2

Purity

≥98%

Formula

C26H24ClN3O3

FormulaWt.

461.95

IUPACName

(3E)-5-Chloro-3-[(5-{3-[(4-methyl-1,4-diazepan-1-yl)carbonyl]phenyl}-2-furyl)methylene]-1,3-dihydro-2H-indol-2-one

ShippingandStorage

StoreTemp

-20°C

ShipTemp

Ambient

Downloads

InfoSheet

C9200InfoSheetPDF

References

PadmanabhanA,GoscEB,BieberichCJ.Stabilizationoftheprostate-specifictumorsuppressorNKX3.1bytheoncogenicproteinkinasePim-1inprostatecancercells.JCellBiochem.2013May;114(5):1050-7.PMID:23129228.

HaddachM,MichauxJ,SchwaebeMK,etal.DiscoveryofCX-6258.APotent,Selective,andOrallyEfficaciouspan-PimKinasesInhibitor.ACSMedChemLett.2011Dec27;3(2):135-9.PMID:24900437.


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