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Cellgs/Recombinant Human Chemerin/Human Chemerin, 25 μg/GFH36-25

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PODS® Growth Factors

This growth factor is also available as PODS® for sustained release, seehere.

Description

Chemerin is a chemoattractant adipokine that is expressed in white adipose, liver, skin, and lung tissues. Chemerin is a ligand for the G protein-coupled receptor chemokine-like receptor 1 (ChemR23), which is expressed on dendritic cells, macrophages, and adipocytes. Chemerin functions to recruit macrophages to sites of tissue damage and inflammation. Chemerin is also a regulator of glucose metabolism in the liver.

Activity Assay

Human Chemerin is fully biologically active when compared to standard. The activity can be determined by its ability to chemoattract human Chem23R transfected BaF3 mouse pro-B cells and it is typically 4 - 20 ng/ml.

AA Sequence

MELTEAQRRG LQVALEEFHK HPPVQWAFQE TSVESAVDTP FPAGIFVRLE FKLQQTSCRK RDWKKPECKV RPNGRKRKCL ACIKLGSEDK VLGRLVHCPI ETQVLREAEE HQETQCLRVQ RAGEDPHSFY FPGQFAFS

Alternative Names

Tazarotene-induced gene 2, TIG2, RARRES2
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Product Details
Length138 aa
Molecular Weight16 kDa
StructureMonomer
SourceE. coli
Accession NumberQ99969
Purity≥95% determined by reducing and non-reducing SDS-PAGE
Endotoxin Level≤1.00 EU/μg as measured by kinetic LAL
FormulationLyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
ReconstitutionCentrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Stability and Storage

12 months from date of receipt when stored at -20°C to -80°C as supplied. 1 month when stored at 4°C after reconstituting as directed. 3 months when stored at -20°C to -80°C after reconstituting as directed.

Documents

GFH36 Datasheet.pdfMSDS Recombinant Proteins.pdf

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