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Haptoglobin,HumanPlasma,MixedType

触珠蛋白

ExtinctionCoefficient:1.20

Salt-freelyophilizedsolid.

Storage:-20°C

Anacute-phaseplasmaproteinfoundinhumanplasmaat100-300mgper100ml.Bindshemoglobin,thuspreventinglossofironthroughthekidneys.Humansarepolymorphicforhaptoglobin,withthreemajorphenotypes:Hp1-1,Hp2-1,andHp2-2.Whilethephenotypicdistributioncanvarygreatlybetweenethnicitiesandgeographiclocation,theHp2-1phenotypeisthemostprevalentphenotypeinhumans.PlasmaconcentrationsofhaptoglobinarehighestinindividualswithHp1-1,intermediateinHp2-1individuals,andlowestinHp2-2individuals.Hp1-1isthemosteffectiveatbindinghemoglobin,andHp2-2istheleasteffective.Thisfunctionaldifferencemaybeassociatedwiththefrequencyandseverityofepilepsyattacks,asresearchershavefoundacorrelationbetweenrecurringseizuresandtheHp2-2phenotype.


Purity:>=95%bySDS-PAGE

PreparedfromplasmashowntobenonreactiveforHBsAg,anti-HCV,anti-HBc,andnegativeforanti-HIV1&2byFDAapprovedtests.

AthensResearch&TechnologyproductsarelaboratoryreagentsandarenottobeadmiNISTeredtohumansorusedforanydrugpurpose.Forresearchuseonly.



MyeloperoxidaseEnzymeImmunoassayKit

髓过氧化物酶免疫分析试剂盒

HumanMPOEIAKITFEATURES:

USE-MeasurehumanMPOinavarietyofmatrices
SAMPLE-Serum,Platelet-PoorHeparinPlasma,Saliva,UrineorTissueCultureMedia
SAMPLES/KIT-40induplicate
SENSITIVITY-0.068ng/mL
STABILITY-liquidreagentsstableat4°C
QUICKRESULTS-2.5HOURS

Myeloperoxidase(MPO)isatetramericheme-containingproteinabundantlyproducedinneutrophilgranulocyteswhereitplaysanimportantanti-microbialrole.DuringdegranulationMPOisreleasedintotheextracellularspace.There,aspartoftheneutrophils“respiratoryburst”,itproduceshypochlorousacidfromhydrogenperoxideandCl–.MPOalsouseshydrogenperoxidetooxidizetyrosinetothetyrosylrADIcal.Bothhypochlorousacidandtyrosylarecytotoxicandwhenpresentcankillbacteriaandotherpathogens.Hereditarydeficiencyofmyeloperoxidasepredisposesindividualstoimmunedeficiency.

StudieshaveshownanassociationbetweenelevatedMPOlevelsandcoronaryarterydisease,andin2003itwassuggestedthatMPOmayserveasasensitivepredictorofmyocardialinfarctioninpatientscomplainingofchestpain.SincethattimetheclinicalutilityofMPOtestingincardiacpatientshasbeensolidlyestablishedintheliteraturewithwellover100paperspublished.In2010thisclinicalapplicationwasfurtherrefinedbyadditionalstudieswhichdeterminedthatmeasuringbothMPOandC-reactiveprotein(CRP)providedmoreaccuratepredictionofmortalityriskthanmeasuringjustCRPalone.


MyeloperoxidaseEnzymeImmunoassayKit

髓过氧化物酶免疫分析试剂盒

HumanMPOEIAKITFEATURES:

USE-MeasurehumanMPOinavarietyofmatrices
SAMPLE-Serum,Platelet-PoorHeparinPlasma,Saliva,UrineorTissueCultureMedia
SAMPLES/KIT-40induplicate
SENSITIVITY-0.068ng/mL
STABILITY-liquidreagentsstableat4°C
QUICKRESULTS-2.5HOURS

Myeloperoxidase(MPO)isatetramericheme-containingproteinabundantlyproducedinneutrophilgranulocyteswhereitplaysanimportantanti-microbialrole.DuringdegranulationMPOisreleasedintotheextracellularspace.There,aspartoftheneutrophils“respiratoryburst”,itproduceshypochlorousacidfromhydrogenperoxideandCl–.MPOalsouseshydrogenperoxidetooxidizetyrosinetothetyrosylradical.Bothhypochlorousacidandtyrosylarecytotoxicandwhenpresentcankillbacteriaandotherpathogens.Hereditarydeficiencyofmyeloperoxidasepredisposesindividualstoimmunedeficiency.

StudieshaveshownanassociationbetweenelevatedMPOlevelsandcoronaryarterydisease,andin2003itwassuggestedthatMPOmayserveasasensitivepredictorofmyocardialinfarctioninpatientscomplainingofchestpain.SincethattimetheclinicalutilityofMPOtestingincardiacpatientshasbeensolidlyestablishedintheliteraturewithwellover100paperspublished.In2010thisclinicalapplicationwasfurtherrefinedbyadditionalstudieswhichdeterminedthatmeasuringbothMPOandC-reactiveprotein(CRP)providedmoreaccuratepredictionofmortalityriskthanmeasuringjustCRPalone.

 


AthensResearch常用产品报价单

产品名货号公司分类商城分类美金价
AthensResearch&Technology/Alpha2Antiplasmin,HumanPlasma/16-16-012901/100ug16-16-012901-100ugcoagulation-factors人体抗原55.00


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