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Myeloperoxidase,HumanNeutrophil
人嗜中性粒细胞髓过氧化物酶
100ug$85
1mg $700
MW:130,000-150,000
ExtinctionCoefficient:1.45
Lyophilizedfrom50mMNaacetate,pH6.0with100mMNaCl
Thishemeproteincatalyzesoxidationsbyhydrogenperoxide,includingMPO-chloridemediatedkillingofmicrobesandtumorcells,inactivationofhemotacticfactors,crosslinkingofproteinsandinclinationofproteins.
Activity:180-220unitspermgproteinafterlyophilization.Oneunitisdefinedastheamountofenzymethatdecomposesoneumoleofhydrogenperoxideperminuteat25oC,pH6.0.Reactionmixturecontains30mMsodiumphosphate,pH6.1,30mMguaiacol,and0.0012%(0.35mM)hydrogenperoxide.
Storage:-20°C
Purity:>=95%bySDS-PAGE
PreparedfromwholebloodshowntobenonreactiveforHBsAg,anti-HCV,anti-HBc,andnegativeforanti-HIV1&2byFDAapprovedtests.
AthensResearch&Technologyproductsarelaboratoryreagentsandarenottobeadministeredtohumansorusedforanydrugpurpose.Forresearchorfurthermanufacturinguseonly.

MyeloperoxidaseEnzymeImmunoassayKit
髓过氧化物酶免疫分析试剂盒
HumanMPOEIAKITFEATURES:
USE-MeasurehumanMPOinavarietyofmatrices
SAMPLE-Serum,Platelet-PoorHeparinPlasma,Saliva,UrineorTissueCultureMedia
SAMPLES/KIT-40induplicate
SENSITIVITY-0.068ng/mL
STABILITY-liquidreagentsstableat4°C
QUICKRESULTS-2.5HOURS
Myeloperoxidase(MPO)isatetramericheme-containingproteinabundantlyproducedinneutrophilgranulocyteswhereitplaysanimportantanti-microbialrole.DuringdegranulationMPOisreleasedintotheextracellularspace.There,aspartoftheneutrophils“respiratoryburst”,itproduceshypochlorousacidfromhydrogenperoxideandCl–.MPOalsouseshydrogenperoxidetooxidizetyrosinetothetyrosylradical.Bothhypochlorousacidandtyrosylarecytotoxicandwhenpresentcankillbacteriaandotherpathogens.Hereditarydeficiencyofmyeloperoxidasepredisposesindividualstoimmunedeficiency.
StudieshaveshownanassociationbetweenelevatedMPOlevelsandcoronaryarterydisease,andin2003itwassuggestedthatMPOmayserveasasensitivepredictorofmyocardialinfarctioninpatientscomplainingofchestpain.SincethattimetheclinicalutilityofMPOtestingincardiacpatientshasbeensolidlyestablishedintheliteraturewithwellover100paperspublished.In2010thisclinicalapplicationwasfurtherrefinedbyadditionalstudieswhichdeterminedthatmeasuringbothMPOandC-reactiveprotein(CRP)providedmoreaccuratepredictionofmortalityriskthanmeasuringjustCRPalone.
苏州蚂蚁淘生物科技有限公司是专业从事生物技术产品销售的高科技企业,是国内生物试剂、仪器、消耗品领域的知名企业之一。起发公司自成立以来,连续2年高速成长。公司的发展目标是建成专业从事生物技术产品销售、生产与开发的一流公司。