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| Catalog No./Size: | GMH0411Z-025/25 Tests GMH0411Z-100/100 Tests | |
| Vol.per.Test: | 10 μl/Test | |
| Clone: | GM1CD41 | |
| Isotype: | Mouse IgG1 | |
| Reactivity: | Human,Not yet tested in other species. | |
| Workshop: | N/A | |
| Storage Buffer: | Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA | |
| Storage Condition: | Store at 4�C.DO NOT FREEZE. LIGHT SENSITIVE MATERIAL. | |
| Applications: | Flow Cytometry | |
| Applications Notes: | FACS: Use 10µl for 106 cells | |
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| Description: | GM1CD41 reacts with a calcium-dependent complex of CD41/CD61 ( GPIIb/IIIa), 135/120 kDa, expressed on normal platelets and megakaryocytes. CD41 antigen acts as a receptor for fibrinogen, von Willebrand factor (vWf), fibrinectin and vitronectin and mediates platelet adhesion and aggregation. GM1CD41 antibody completely inhibits ADP, epinephrine and collagen-induced platelet activation and partially inhibits restocetin and thrombin-induced platelet activation.�It is useful in the morphological and physiological studies of platelets and megakaryocytes. | |