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Genemay/Mouse antiHuman CD29, FITC Conjugated mAb./GMH0291F/100 Tests

Product Details

Catalog No./Size: GMH0291F-025/25 Tests
GMH0291F-100/100 Tests
Vol.per.Test: 10 μl/Test
Clone: GMCD29
Isotype: Mouse IgG1
Reactivity: Human,Not yet tested in other species.
Workshop: N/A
Storage Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Storage Condition: Store at 4�C.DO NOT FREEZE. LIGHT SENSITIVE MATERIAL.
Applications: Flow Cytometry
Applications Notes:

FACS: Use 10µl for 106 cells

Description:

GMCD29 reacts with 130 kDa integrin b1 , which has a broad tissue distribution . It is expressed on lympnocytes , monocytes and weakly on granulovytes, but not on erythrocytes. On T cells, CD29 is more highly expressed on memory cells than naive cells. Integrin chain b asociated with integrin a subunits 1-6 ( CD49a-f) to form CD49/CD29 heterodimers that are involved in cell-cell and cell-matrix adhesion.It has been reported that CD29 is a critical molecule for embryogenesis and development. It also essential to the differentiation of hematopoietic stem cells and associated with tumor progression and metastasis.This clone is cross reactive with non-human primate .


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