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MD Bioproducts/ST2L Monoclonal Antibody, Biotinylated/101002B/200 uL

Overview: 

T1/ST2(alsoknownasIL-1R4orIL-33Ra)isatransmembraneglycoproteinexpressedonmastcellsandTh2cells.ItisaselectiveMarkerforbothmurineandhumanTh2lymphocytesandplaysaroleinregulatinginflammatoryresponses.IL-33isarecentlyidentifiedmemberoftheIL-1familyofcytokinesandisinvolvedinTh2mediatedimmuneresponses.IL-33mediatesitsBIOLOGicaleffectsviaT1/ST2binding.TherolesofIL-33andT1/ST2(IL-33Ra)havebeeninvestigatedinmanyimmuneresponsessuchasallergy,asthma,rheumatoidarthritisandosteoarthritis.

Data/Specifications: 

Clone:B4E6

 

IgGSubclass: IgG1

 

Form:ThebiotinylatedantibodyissuppliedinPBSandpurifiedoverproteinG-sepharosefrom concentratedtissueculturesupernatant.Theantibodyissuppliedwith0.1%sodiumazideas preservative.

 

Specificity:ThisclonerecognizeshST2Lspecificallyonthecellsurfaceofhumantype2(Th2,Tc2,NK2and NKT2)butnottype1lymphocytes.

How_To_Use:

 

Applications

  • Flowcytometry
  • FACS
  • cellsorting
  • immunohistochemistrywithhybridomaculturesupernatant

 

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