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Neuromics/Frizzled 4/CD344/GT15217/100 ug

Type:GoatIgG

 

Applications:IHC;WB;E

E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssays

SpeciesReactivity:M

B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;All

Format:AffinityPurified-liquid

 

Immunogen:Purified,NS0-derived,recombinantmouseFrizzled-4(rmFrizzled-4)extracellularCysteine-RichDomain(CRD).

 

Picture

Frizzled4,alsoknownasFZD4andCD344,  isaneuronalstemcellMarker. Thisincludesexpression onfetalneuronalProgenitorcellsandneuronalintestinalcells.Transcriptshavealsobeenidentifiedinliver,kidney,pancreas,spleen,andfetallung,andinsmalleramountsinplacenta,adultlung,prostate,testisandcolon.

Ithasbeenreportedthat itcontrolsretinalandinnerearangiogenesis,participatesintheregulationofembryonicdevelopment,tissueandcellpolarizationandproliferation.

Image:FZD4staining ofE18MouseNeuronalTissue.  Tissuewasstained withgoatHRP-DAB(brown)andcounterstainedwithHematoxylin(blue).Dilution:15µg/mL.

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