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Mabtech/Mouse IL-12/-23 (p40) ELISA development kit (HRP)/3451-1H-20/for 20 plates188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Mabtech/Mouse IL-12/-23 (p40) ELISA development kit (HRP)/3451-1H-20/for 20 plates

ELISAdevelopmentkitforquantificationofIL-12/-23(p40)insolution

ThemouseIL-12/-23(p40)ELISAdevelopmentkitisidealforuserswhowanttheflexibilityofsettinguptheirownELISAassay.ThisproductenablesquantificationofmouseIL-12/-23(p40)insolution,e.g.incellculturesupernatant.Thekitcontainsamatchedpairofmonoclonalcaptureanddetectionantibodies,Streptavidin-HRPandELISAstandard.Platesandsubstratearenotincluded.

Themonoclonalantibodiesinthiskitarespecifictothep40subunitofIL-12andIL-23.ELISAassaysbasedonantibodiestop40willdetectbothIL-12andIL-23.Suchassayscanalsodetectp40monomersanddimers.

MouseIL-12/-23(p40)ELISAdevelopmentkitsarealsoavailablewithStreptavidin-ALP.SeeRelatedproducts.

ELISAsubstrate

Ready-to-useELISAsubstrateisavailableinourwebshop.SeeRelatedproducts.

AnalyteInformation

IL-12/-23(p40)
Interleukin-12(IL-12,IL12)is,whenBIOLOGicallyactive,aheterodimer(p70)consistingoftwocovalentlylinkedsubunits,p35andp40.IL-12isproducedbyantigen-presentingcells,specificallydendriticcellsandmacrophages.IL-12isaproinflammatorycytokinethatpromotesTh1-typeresponsesbyinducingIFN-γproductionandenhancingproliferationandcytotoxicityofNKandTcells.Interleukin-23(IL-23)isadisulfide-linkedheterodimerwhichconsistsofauniquep19subunitandthep40subunitofIL-12.IL-23isaproinflammatorycytokine,whichisproducedbymacrophagesanddendriticcellsuponinfectionswithcertainpathogens.TheIL-23receptorisexpressedonTh17cellsandIL-23isresponsIBLeforTh17expansionandstABIlization.SincebothIL-12andIL-23heterodimerscomprisethep40subunit,captureimmunoassaysbasedonantibodiestop40willdetectbothcytokines.Suchassayscanalsodetectp40monomersanddimers.

Application:
  • ELISA
Reactivity:
  • Mouse
Standardrange:10-1000pg/ml
Contents:
  • CapturemAb(C15.6)
  • BiotinylateddetectionmAb(C17.8)
  • Streptavidin-HRP
  • RecombinantmouseIL-12p70ELISAstandard
Size:for20plates
Otherformats:ClicktoviewallMouseIL-12/-23(p40)products
Savetimeandreducevariabilitywiththe
completeandpre-coatedELISAPROkit
Mabtechserviceishighlycustomer-friendlyandefficient.WehavebeenusingMabtechELISAkitsforthepasteightyearswithfullsatisfaction.FurThermore,IfindMabtechproductsthebestforevendevelopingmyin-houseELISA.
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