| Synonyms | MonoclonalTLR8antibody,Anti-TLR8antibody,TLR-8antibody,Tolllikereceptor8antibody,TLR8,TLR8,TLR-8,TLR8antibody,TLR-8antibody |
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| CrossReactivity | Human |
| Applications | WB |
| Immunogen | TLR8antibodywasraisedinMouseusingrecombinanthumanTLR8astheimmunogen. |
| Host | Mouse |
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| Clone | 44B05 |
| Isotype | IgG1 |
| MethodofPurification | TLR8antibodywaspurifiedbyProteinGpurification. |
| Form&Buffer | SuppliedinPBSbuffer,pH7.2,containing50%glycerol,1%BSA,0.02%thimerosal. |
| Concentration | 1mg/ml |
| Storage | Storeat-20degC.Forlong-termstorage,aliquotandfreezeat-70degC.Avoidrepeatedfreeze/thawcycles. |
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| UsageRecommendations | WB:1:200-1000 |
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| BiologicalSignificance | TheTolllikereceptor(TLR)familyinmammaliancomprisesafamilyoftransmembraneproteinscharacterizedbymultiplecopiesofleucinerichrepeatsintheextracellulardomainandIL1receptormotifinthecytoplasmicdomain.Uptodate,tenTLRs(TLR110)havebeendescribed.TLR8genecontainsthreeexons,twoofwhichhavecodingfunction.ExpressionofTLRreceptorsishighestinperipheralbloodleukocytes,macrophages,andmonocytes. |
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