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| Synonyms | Monoclonal BNP antibody, Anti-BNP antibody, Natriuretic peptide brain type antibody, BNP 32 antibody, Brain Natriuretic Peptide antibody, Brain natriuretic peptide 32 antibody, NPPB antibody, NPPB protein antibody, Natriuretic peptides B antibody, gamma brain natriuretic peptide antibody, Natriuretic peptide precursor B antibody |
|---|---|
| Cross Reactivity | Human |
| Applications | ELISA, IHC |
| Immunogen | BNP antibody was raised in Mouse using synthetic peptide corresponding to aa (Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser) of human BNP, conjugated to KLH as the immunogen. |
| Host | Mouse |
|---|---|
| Clone | 8D5B4C11 |
| Isotype | IgG1 |
| Form & Buffer | Supplied as a liquid in ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1.0 mg/ml |
| Storage | Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Usage Recommendations | ELISA: 1:10,000, IHC: 1:200-1:1000 |
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| Biological Significance | Brain natriuretic peptide (BNP) circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. BNP is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. BNP belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C type natriuretic peptide (CNP) and urodilatin. |
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