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| Synonyms | Monoclonal Neu antibody, Anti Neu antibody, Neu antibody, Neu Oncogene antibody, Neu Oncogene antibody, Neu-Oncogene antibody, Anti Neu antibody, Neu-Oncogene antibody |
|---|---|
| Cross Reactivity | To be determined by the end user |
| Applications | IHC, WB |
| Immunogen | Neu antibody was raised in mouse using synthetic peptide (internal domain of the c-erbB-2 oncoprotein) as the immunogen. |
| Host | Mouse |
|---|---|
| Clone | CB11 |
| Isotype | IgG1 |
| Form & Buffer | Supplied in liquid form. Dilute with PBS with 1% BSA and 0.1% Na-Azide |
| Storage | Store at 2-8 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Usage Recommendations | IHC: 1:5 - 1:10 |
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| Biological Significance | neu-Oncogene reacts with the 185 kD protein in immunoblot-ting. The c-erbB2 proto-oncogene codes for a membrane protein. Several studies report the amplification in carcinomas. Overexpression of c-erbB-2 in breast cancer is a marker for poor prognosis. |
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