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| Synonyms | MonoclonalPAIP2antibody,Anti-PAIP2antibody,PAIP2Aantibody,PABP-interactingprotein2antibody,HSPC218antibody,Poly(A)-bindingprotein-interactingprotein2poly(A)antibody,Bindingproteininteractingprotein2antibody,PAIP2antibody,PAIP-2antibody |
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| Applications | ELISA,WB |
| Immunogen | PAIP2antibodywasraisedinMouseusingrecombinanthumanPAIP2(1-127aa)purifiedfromE.coliastheimmunogen |
| Host | Mouse |
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| Clone | AT1C12 |
| Isotype | IgG2b |
| MethodofPurification | PAIP2antibodywaspurifiedbyproteinGaffinitychromatography |
| Form&Buffer | SuppliedinliquidforminPhosphate-BufferedSaline(pH7.4)with0.1%SodiumAzide |
| Concentration | 1mg/ml |
| Storage | Storeat4degCforupto2weeks.Forlongtermstorage,aliquotandstoreat-20degCto-70degC.Avoidrepeatedfreeze/thawcycles |
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| UsageRecommendations | WB:1:500-1:5000 |
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| BiologicalSignificance | PAIP2(Poly(A)-bindingprotein-interactingprotein2)isa127aminoacidprotein.PAIPbindstothepolyadenylate-bindingprotein(PABP).TherearetwoPAIPproteinscalledPAIP1andPAIP2.PAIP2actsasarepressorintheregulationoftranslationinitiationofpoly(A)-containingmRNAs.andPaip1stimulatestranslation.PAIP2containstwobindingsitesforPABP,oneencompassinga16-amino-acidstretchlocatedintheCterminusandasecondencompassingalargercentralregion. |
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