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| Synonyms | Monoclonal TMEFF2 antibody, Anti-TMEFF2 antibody, CT120.2 antibody, HPP1 antibody, TENB2 antibody, TPEF antibody, TR antibody, transmembrane protein with EGF-like and two follistatin-like domains 2 antibody, TMEFF2, TMEFF 2, TMEFF-2, TMEFF 2 antibody, TMEFF-2 antibody |
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| Cross Reactivity | Human |
| Applications | IHC, WB |
| Immunogen | TMEFF2 antibody was raised in Mouse using full length human recombinant protein of human TMEFF2 produced in HEK293T cell as the immunogen. |
| Host | Mouse |
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| Clone | 1B4 |
| Isotype | IgG2a |
| Method of Purification | TMEFF2 antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 0.5-1 mg/ml |
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Usage Recommendations | IHC: 1:150, WB: 1:2000 |
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| Biological Significance | TMEFF2, a gene encoding a plasma membrane protein with two follistatin-like domains and one epidermal growth factor?like domain, had limited normal tissue distribution and was highly overexpressed in prostate cancer. The shedded form up-regulates cancer cell proliferation, probably by promoting ERk1/2 phosphorylation. Down-regulated in tumor cell lines in response to a high level of methylation in the 5 region. |
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