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| Synonyms | Monoclonal LOX antibody, Anti-LOX antibody, Lysyl oxidase antibody, MGC105112 antibody, Protein lysine 6 oxidase antibody, Monoclonal LOX antibody, Anti-LOX antibody, Lysyl oxidase antibody, MGC105112 antibody, Protein lysine 6 oxidase antibody |
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| Cross Reactivity | Human |
| Applications | FC, IF, WB |
| Immunogen | LOX antibody was raised in mouse using a human recombinant protein fragment corresponding to amino acids 22-168 of human LOX (NP_002308) produced in HEK293T cells, as the immunogen. |
| Host | Mouse |
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| Clone | 3C3 |
| Isotype | IgG1 |
| Method of Purification | LOX antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 500 ug-1 mg/ml |
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
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| Usage Recommendations | FC: 1:100, IF: 1:100, WB: 1:2000 |
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| Biological Significance | LOX is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, The encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutislaxa type I (CL type I). |
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