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| Synonyms | MonoclonalPPM1Bantibody,Anti-PPM1Bantibody,Proteinphosphatase1Bisoform3antibody,proteinphosphataseMg2+/Mn2+dependent1Bantibody,proteinphosphatase1B(formerly2C)magnesium-dependentantibody,betaisoformantibody,PPC2betaXantibody,PP2CBantibody,PP2Cbetaantibody,proteinphosphatase2Cantibody,betaisoformantibody,PPM1B,PPMB1,PPMB-1,PPMB1antibody,PPMB-1antibody |
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| CrossReactivity | Human |
| Applications | FC,WB |
| Immunogen | PPM1BantibodywasraisedinmouseusingafulllengthrecombinantproteinofhumanPPM1B(NP_002697)producedinHEK293Tcells,astheimmunogen. |
| Host | Mouse |
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| Clone | 2H5 |
| Isotype | IgG2b |
| MethodofPurification | PPM1Bantibodywaspurifiedbyaffinitychromatography. |
| Form&Buffer | SuppliedinPBSbuffer,pH7.3,containing1%BSA,50%glyceroland0.02%sodiumazide. |
| Concentration | 500ug-1mg/ml |
| Storage | Storeat4degCforshorttermstorage.Aliquotandstoreat-20degCforlongtermstorage.Avoidrepeatedfreeze/thawcycles. |
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| UsageRecommendations | FC:1:100,WB:1:2000 |
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| BiologicalSignificance | Proteinphosphatase1B(PPM1B)isamemberofthePP2Cfamilyofserine/threonineproteinphosphatases.PP2Cfamilymembersareknowntobenegativeregulatorsofcellstressresponsepathways.Thisphosphatasehasbeenshowntodephosphorylatecyclin-dependentkinases,andthusmaybeinvolvedincellcyclecontrol.Overexpressionofthisphosphataseisreportedtocausecell-growtharrestorcelldeath. |
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