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| Synonyms | MonoclonalCD133antibody,Anti-CD133antibody,PROM1antibody,AC133antibody,CD133antibody,CORD12antibody,MCDR2antibody,PROML1antibody,RP41antibody,STGD4antibody,Prominin1antibody,AC133antibody,CD133antibody,CD-133antibody,CD133 |
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| CrossReactivity | Mouse |
| Applications | FC,IHC,IP,WB |
| Immunogen | CD133antibodywasraisedinRatusingmouseProminin1(CD133)astheimmunogen |
| Host | Rat |
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| Clone | 13A4 |
| Isotype | IgG1kappa |
| MethodofPurification | CD133antibodywaspurifiedusingproteinApurification |
| MolecularWeight | 115kDa |
| Form&Buffer | Suppliedinliquidformin20mMsodiumphosphate,250mMNaCl,pH.7.6,with0.1%sodiumazideasapreservative |
| Concentration | 1.0mg/ml |
| Storage | Stablefor1yearat2-8degC |
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| UsageRecommendations | IHC:1-15ug/ml |
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| BiologicalSignificance | CD133isexpressedinhematopoieticstemcells,endothelialprogenitorcells,glioblastoma,neuronalandglialstemcells,variouspediatricbraintumors,aswellasadultkidney,mammaryglands,trachea,salivaryglands,placenta,digestivetract,testes,andsomeothercelltypes.RecentstudiesinbraintumorshaveidentifiedaCD133+cellpopulationthoughttobeacancerstemcellpopulation,whichisrare,undergoesself-renewalanddifferentiation,andcanpropagatetumorswheninjectedintoimmune-compromisedmice.However,subsequentstudieshaveindicatedthedifficultyinisolatingpureCSCpopulations. |
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