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bioporto/Recombinant Mouse NGAL/1kit/SP002RA

Cat. No.
SP002RA
Purification
This product is purified full length recombinant protein without any tags, produced from E. coli
Production
E. coli
Source
Full length amino acid sequence
Unit Size, Concentration
1 mL, 1000 pg/mL +/-15%
Form
Liquid
Solvent
0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl, 0.5% BSA; 0.5%Tween 20; 0.0016% Phenol red; 0.1% Proclin 950
Storage
2-8°C
Background
Mouse neutrophil gelatinase-associated lipocalin (NGAL; also called lipocalin 2, 24p3, SIP24,uterocalin and siderocalin) is a member of the lipocalin family of proteins which bind andtransport small lipophilic molecules. 24p3 was observed to be dramatically upregulated inkidney cell cultures infected with SV40 (1) and subsequently identified as a lipocalin (2). Unlike human NGAL, it is an acute phase protein upregulated in the liver (3), but like itsmammalian homologues it is upregulated and secreted by the kidney in response to ischemicor nephrotoxic injury (4). It is also upregulated in the involuting uterus and mammary gland. (5)
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