FabGennix/CD4 Antibody/CD4-112AP

General Information

Product

CD4 Antibody

Description

Affinity Purified T-cell surface glycoprotein CD4Antibody C-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide corresponding to Human CD4 aa 437-458 (C terminal). The selected peptide was post-synthetically modified to achieve highest antigenicity before couplingto carrier protein using hetero bifunctional cross linker for Immunogen preparation.

Sequence:

RLLSEKKTCQCPHRFQKTCSPI

Accession #

NCBI: NP_000607.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500. Predicted Molecular weight: 51 kDa

CD4-112AP labels a band of 28 kDa, the identity of this band is not fully understood, but may represent a proteolytic degradation product of CD4.

Protein

Uniprot #

P01730

Overview

Accesory protein for MHC class-II antigen/T-cell receptor interaction.

Molecular Function

Adaptive Immunity; Host-virus interaction; Immunity

Subcellular Location

Cell membrane; Single-pass type I membrane protein

Structure

Contains 3 Ig-like C2-type domains; Contains 1 Ig-like V-type domain

Alternative Nomenclature

CD 4 antibody

CD4 (L3T4) antibody

CD4 antigen (p55) antibody

CD4 antigen antibody

CD4 molecule antibody

CD4 receptor antibody

CD4+ Lymphocyte deficiency, included antibody

CD4mut antibody

L3T4 antibody

Leu3 antibody

Ly-4 antibody

Lymphocyte antigen CD4 antibody

p55 antibody

T cell differentiation antigen L3T4 antibody

T cell OKT4 deficiency, included antibody

T-cell surface antigen T4/Leu-3 antibody

T-cell surface glycoprotein CD4 antibody

W3/25 antigen antibody