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| Species | Human |
|---|---|
| SampleType | Serumorplasma.ForthequantitativedeterminationofhumanHaptoglobinlevelsinserumorotherBIOLOGicalsamples.Blood,PathologicProcesses,HematologicDiseases,BloodCells,Liver. |
| ProductName | HumanHaptoglobin. |
| SampleType | Serumorplasma. |
| #ofSamples | 10X96wells. |
| StorageandStABIlity | -20°C. |
| RangeofDetection | 7.8-500ng/ml. |
| Shelflife | Oneyearfromdateofreceipt. |
| AssayCondition | ThekitperformancehasbeenoptimizedfortheprotocolandmaterialslistedbelowusingstandarddilutionsofhumanHaptoglobininthe7.8-500ng/mlrange.Theoperatormustdetermineappropriatedilutionsofreagentsforalternativeassayconditions.ELISAassayreactivityissensitivetovariationsinoperator,pipettingandwashingtechniques,incubationtime,temperature,compositionofreagents,andotherexperimentalvariables.Assayoptimizationmayberequiredtogeneratethestandardcurveandfitthesamplesinthespecifieddetectionrange. |
| CountryofOrigin | UnitedStatesofAmerica. |
| AssayUse | ForResearchUseOnly(RUO).Notfordiagnosticortherapeuticuseinhumansoranimals.Notforanimalorhumanconsumption. |
| Function | Haptoglobincombineswithfreeplasmahemoglobin,preventinglossofironthroughthekidneysandprotectingthekidneysfromdamagebyhemoglobin,whilemakingthehemoglobinaccessIBLetodegradativeenzymes. |
| Subunit | Tetrameroftwoalphaandtwobetachains. |
| SubcellularLocation | Secreted. |
| TissueSpecificity | Expressedbytheliverandsecretedinplasma. |
| Polymorphism | Inthehumanpopulationstherearetwomajorallelicforms,alpha-1with83residuesandalpha-2with142residues.Theseallelesdeterminethe3majorphenotypesHP*1F/HP*1SandHP*2FS.ThetwomainallelesofHP*1arecalledHP*1F(fast)andHP*1S(slow). |
| Similarity | BelongstothepeptidaseS1family[viewclassification]. Contains1peptidaseS1domain[viewclassification]. Contains2Sushi(CCP/SCR)domains. |
| Name | HumanHaptoglobinELISAQuantitationKit |
|---|---|
| RelatedProductNames | HP2-ALPHA,HumanHaptoglobinELISAKit,HumanHaptoglobin,HP |
| NCBIAccNumber | NP_001119574.1 |
| MolecularWeight | 45205 |
| SwissProtNumber | P00738 |
| IntendedUse | ResearchUseOnly |