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LKT/DUTASTERIDE/D8276/25 mg
ProductIDD8276
CasNo.164656-23-9
Purity≥99%
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

Dutasterideisaninhibitorof5-α-reductase(types1/2)thatisclinicallyusedtotreatbenignprostatichyperplasia(BPH),oftenco-administeredwithtamsulosin.Dutasterideexhibitsanti-inflammatoryandanticancerchemotherapeuticactivities.Inprostaticcells,dutasterideinducesapoptosisandinhibitscellproliferation.Invivo,thiscompounddecreasesprostatevolume.Inanimalmodels,dutasteridesuppressesgrowthofprostatetumors.

ProductInfo

CasNo.

164656-23-9

Purity

≥99%

Formula

C27H30F6N2O2

FormulaWt.

528.53

Synonym

Avodart

Appearance

Whitetooffwhitepowder

ShippingandStorage

StoreTemp

-20°C

ShipTemp

Ambient

Downloads

InfoSheet

D8276InfoSheetPDF

References

TsujimuraA,FukuharaS,SodaT,etal.Histologicevaluationofhumanbenignprostatichyperplasiatreatedbydutasteride:astudybyxenograftmodelwithimprovedseverecombinedimmunodeficientmice.Urology.2015Jan;85(1):274.e1-8.PMID:25444635.

BarkinJ.Reviewofdutasteride/tamsulosinfixed-dosecombinationforthetreatmentofbenignprostatichyperplasia:efficacy,safety,andpatientacceptability.PatientPreferAdherence.2011;5:483-90.PMID:22003286.

ArenaF.Dutasterideinthetreatmentofhormonerefractoryprostatecancer.MinervaUrolNefrol.2008Jun;60(2):71-6.PMID:18500220.


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