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LKT/SOFOSBUVIR/S5722/5 mg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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LKT/SOFOSBUVIR/S5722/5 mg
ProductIDS5722
CasNo.1190307-88-0
Purity≥98%
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

SofosbuvirisanantiviralcompoundthatinhibitsviralRNApolymerase.SofosbuvirisclinicallyusedtotreathepatitisCinfection.Thiscompoundisaprodrugthatismetabolizedtoamoreactiveintermediate.

ProductInfo

CasNo.

1190307-88-0

Purity

≥98%

Formula

C22H29FN3O9P

FormulaWt.

529.45

IUPACName

propan-2-yl(2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate

Appearance

Yellowtooffwhitepowder

ShippingandStorage

StoreTemp

Ambient

ShipTemp

Ambient

Downloads

InfoSheet

S5722InfoSheetPDF

References

MurakamiC,MeldaUrekliH,AttaMG.AntiviralmedicationsforthetreatmentofhepatitisBandCinfectionandtheireffectsonkidneyfunction.MinervaGastroenterolDietol.2014Sep;60(3):177-89.PMID:25027705.

FungA,JinZ,DyatkinaN,etal.Efficiencyofincorporationandchainterminationdeterminestheinhibitionpotencyof2-modifiednucleotideanalogsagainsthepatitisCviruspolymerase.AntimicrobAgentsChemother.2014Jul;58(7):3636-45.PMID:24733478.

MurakamiE,TolstykhT,BaoH,etal.MechanismofactivationofPSI-7851anditsdiastereoisomerPSI-7977.JBiolChem.2010Nov5;285(45):34337-47.PMID:20801890.


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