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Molecular Innovations/Rabbit anti mouse tPA IgG fraction/ASMTPA-GF/10-mg

ProductDescription

RabbitantimousetPAIgGfraction

Polyclonalantibody(hostrabbit).IgGfractionpurifiedbyimmobilizedProteinA.

GeneID:18791
Swiss-Prot/UniProtID:P11214

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AdditionalInformation

Purity

IgGfraction

Source

Rabbitserum

MolecularWeight

160,000

TargetMolecularWeight

70,000

ExtinctionCoefficient

1.36

Antigen

Recombinantfulllengthwild-typemouseprotein(Glycosylated).

Epitope

RecognisesTissuePlasminogenActivator(tPA)

CrossReactivity

Ms,Rat

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species

Mouse

Storage

-70C

ShippingConditions

Dryice

Expiration

5yearsfromdelivery

Form

Frozenliquid

Buffer

0.05MSodiumPhosphate;0.1MNaCl;1mMEDTA;pH6.6

SampleSize

1.0mg

SampleConcentration

10.0mg/ml

SampleVolume

0.1ml

Applications

ELISA,Immunohistochemistry(frozensections),Immunoprecipitation,WesternBlot

GeneName

PLAT

GeneID

18791

UniProtID

P11214

1.ZaitsevS,DanielyanK,MurcianoJCet-al.Humancomplementreceptortype1-directedloADIngoftissueplasminogenactivatoroncirculatingerythrocytesforprophylacticfibrinolysis.Blood.2006;108(6):1895-902.doi:10.1182/blood-2005-11-012336–Freetextatpubmed–Pubmedcitation

2.AdhamiF,YuD,YinWet-al.Deleteriouseffectsofplasminogenactivatorsinneonatalcerebralhypoxia-ischemia.Am.J.Pathol.2008;172(6):1704-16.doi:10.2353/ajpath.2008.070979–Freetextatpubmed–Pubmedcitation

3.SundaramJR,ChanES,PooreCPet-al.Cdk5/p25-inducedcytosolicPLA2-mediatedlysophosphatidylcholineproductionregulatesneuroinflammationandtriggersneurodegeneration.J.Neurosci.2012;32(3):1020-34.doi:10.1523/JNEUROSCI.5177-11.2012–Pubmedcitation

4.BiohS,SuhN,KimI,LeeJY.Impactsofagingandamyloid-βdepositiononplasminogenactivatorsandplasminogenactivatorinhibitor-1intheTg2576mousemodelofAlzheimer’sdisease.BrainRes.2015;1597:159-67.–linktoarticle

5.CooperJM,RastogiA,KrizoJA,MintzEM,ProsserRA.Urokinase-typeplasminogenactivatormodulatesmammaliancircadianclockphaseregulationintissue-typeplasminogenactivatorknockoutmice.EurJNeurosci.2016;Linktoarticle

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