Innovative Research/Human ACE ELISA Kit/IRKTAH5000/1 Ea

ProductDescription

HumanACEELISAKit-1Kit(96Wells)

OurHumanACEELISAKitisasandwichELISAintendedforthequantitativedeterminationofhumanACEincellculturesupernates,serum,plasma(heparin)andsaliva.

Angiotensin-convertingenzyme(ACE)isazinc-containingdipeptidylcarboxypeptidasewidelydistributedinmammaliantissuesandisthoughttoplayacriticalroleinbloodpressureregulation.Thepredictedproteinisidentical,fromresidue37toitsCterminus,tothesecondhalforC-terminaldomainoftheendothelialACEsequence.Theproteinsequenceinferredconsistsofa732-residuepreproteinincludinga31-residuesignalpeptide.Thematurepolypeptidehasamolecularweightof80,073.AlthoughACEhasbeenstudiedprimarilyinthecontextofitsroleinbloodpressureregulation,thiswidelydistributedenzymehasmanyotherphysiologicalfunctions.TheACEgeneencodestwoisozymes.Thesomaticisozymeisexpressedinmanytissues,includingvascularendothelialcells,renalepithelialcells,andtesticularLeydigcells,whereasthetesticularorgerminalangiotensin-convertingenzymeisexpressedonlyinsperm.ThestandardproductusedinthiskitisrecombinanthumanACE,consistingof30-1261aminoacidswiththemolecularmassof120KDa.

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