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NeoBio该MAb与CD56 / NCAM的细胞外结构域(接近跨膜)反应。神经细胞粘附分子(NCAM)的三种同工型是通过单个基因的RNA转录物的差异剪接产生的。135kDa亚型是基本分子,被糖基化或唾液酸化以生成成熟物种。抗CD56识别神经细胞粘附分子的两种蛋白质,即在大多数神经外胚层衍生的组织和肿瘤(例如视网膜母细胞瘤,髓母细胞瘤,星形细胞瘤,神经母细胞瘤和小细胞癌)中表达的基本分子。它也在某些中胚层衍生的肿瘤(横纹肌肉瘤)中表达。抗CD56在淋巴结和鼻NK / T细胞淋巴瘤的诊断中起重要作用。
NeoBio该MAb与脂联素(一种脂细胞因子)反应。脂肪细胞因子是在脂肪组织中产生的激素。脂联素大量存在于血浆中,并且对血液中的葡萄糖水平具有类似胰岛素的作用。肥胖,患有2型糖尿病或HIV脂肪营养不良的胰岛素抵抗患者的血浆脂联素水平较低。女性的脂联素水平往往高于男性,这可能是由于雄激素抑制了脂联素水平。此外,脂联素和瘦素均通过对下丘脑的直接作用来调节体重,影响食欲。肥胖者的脂联素水平较低,而厌食症患者的脂联素水平较高。脂联素可作为多种受体的配体,其中两种已被确定,一种可能参与了碳水化合物的同化作用,

NeoScientific is a dynamic and growing provider of high quality biology research reagents, tools, and custom services. From our headquarters in the heart of the Boston Biotech Cluster we support the needs of academic and industry clients for custom-made proteins, antibodies and peptides. In addition, we maintain a large catalog of unique and highly sensitive ELISA kits, and ready-made proteins, peptides, antibodies, and cell culture products.
Our goal is to provide the highest quality research reagents and services for reasonable costs allowing our customers to focus their precious time and resources on advancing their own research. We provide our customers with the critical reagents they need more rapidly and in a more cost-effective manner than can be done in their own labs.
To provide the most effective support we are constantly seeking out new technologies that speed up project delivery, drive down cost, and improve quality. Such improvements include the recent introduction of our MassAb™ platform that produces a panel of monoclonal antibodies against a single target protein at greatly reduced per antibody costs. In addition, we also produce no-risk custom polyclonal antibodies that customers can receive at no cost for evaluation in their own systems.
苏州蚂蚁淘生物科技有限公司成立于2017年,致力于将全球领先的创新产品和前沿技术带入中国,帮助国内科研工作者在第一时间接触世界范围内的技术革命,并分享研发工具的进步带来的技术红利。依托于集团公司深厚的资源和超过400家的国内优质客户群体,生命科学领域的一站式供应链体系,以及高风险生物危险材料进出口平台的优势,蚂蚁淘生物严格筛选国际创新且经过同行验证过的产品和技术,引入中国市场,开发、孵育和推广。公司的未来将立足于实验室大数据整合和电子商务,结合严格的品牌筛选、创新的营销模式、专注的应用支持和坚实服务,帮助实现生命科学产业链的简单和高效。