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2016年2月14日Biotech Support Group(BSG)代理商,苏州达麦迪生物医学科技有限公司 客服热线:4006-400-850 美国BSG(Biotech Support Group''LLC)公司是一家公司是一家全球知名...

Biotech Support Group Biotech Support Group LLC 成立于 2004 年。公司的使命是服务于蛋白质组样品制备的爆炸性增长,具有独特和专有的表面化学。致力于创造新的方法和应用,为所有下游蛋白质组学...

风险提示:蚂蚁淘仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。

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Biotech Support Group(BSG)代理商,苏州达麦迪生物医学科技有限公司

客服热线:4006-400-850

美国BSG(Biotech Support Group\LLC)公司是一家公司是一家全球知名的蛋白质组和基因组样本预处理的公司,是这个领域公认的领导者,该公司将其发明的专利表面化学技术应用生物学领域,比其他方法如亲合技术,苯酚法有绝对的优势。由于技术上的领先,使得BSG公司的产品广泛被美国国家基因组研究所,斯坦福大学等重要机构使用。(http://www.biotechsupportgroup.com/)

Nature Article Cites HemogloBind and NRicher for Macromolecular Complex Annotation

MONMOUTH JUNCTION, NJ, February 9, 2016 -- Biotech Support Group reports on a recent research article published in Nature, describing the simplicity and efficiency of their proteomic enrichment technology to observe and annotate soluble multiprotein complexes common to metazoa.


The citation is:

C Wan, B Borgeson, S Phanse, F Tu, K Drew, G Clark, et al. Panorama of ancient metazoan macromolecular complexes. Nature 525, 339 344 (17 September 2015).

doi:10.1038/nature14877


In brief, the article s authors aimed at elucidating the components of multiprotein complexes on a proteome-wide scale. The authors identify protein complexes from nine species in parallel, based on biochemical fractionation of native soluble macromolecular complexes followed by tandem mass spectrometry to identify components. The article states clarified heart and liver homogenates were frozen, and subsequently pooled, depleted of hemoglobin using HemogloBind according to manufacturer s instructions prior to sucrose gradient fractionation. A second Biotech Support Group product, formerly called SeraFILE PROspector and now trademarked as NRicher 6, was used for sub-proteome enrichment. The article states Affinity bead based sample pre-separations were performed forC. elegans lysates as per manufacturer s instructions fractions (SeraFILE bead eluates) were subjected to ion exchange fractionation . The authors conclude that many complexes are conserved across species, and by correlating the results with genome sequence information, are able to predict more than one million interactions in 122 eukaryotes.

I am very pleased that two of our products were able to contribute to this rigorous examination of protein complexes. When our products were used as a pretreatment step in the overall workflow, about twice the number of observations and annotations became possible. This further validates that the sub-proteome bias characteristics of NRicher 6 can simplify complex proteomes into less complex sub-proteomes with efficiencies suitable for deep functional proteome characterization. Furthermore, this study demonstrated the importance of a key feature implicit to all of our products; that is the maintenance of functional and structural integrity after separations. Without that particular feature, these additional observations would not have been possible. states Swapan Roy, Ph.D., President and Founder of Biotech Support Group.

For more information on HemogloBind , visit:

http://www.biotechsupportgroup.com/HemogloBind-Hemoglobin-Depletion-From-Hemolyzed-p/h0145.htm


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