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Removes30 mg albumin/ml, >90%
Affinity-typeequivalence, virtually no cross-reactivity with other proteins
Disposable,no column regeneration or cross-contamination
Economicalnew surface technology, not based on blue-dye or immuno-affinitychromatography
Mildbinding conditions maintains tertiary structure and simple transferto secondary analysis
Theflow-through (unbound) fractions retain their enzymatic andbiological activity
Removesalbumin from most species including human, sheep, bovine, mouse,goat, rat, and calf.
Validatedin the automation compatible high-throughput DPX Technologies XTRtip format
Poly-electrolytesare polymers with repeating units of stationary charges.AlbuSorb™comes from a class of solid-phase, or bead-based, elastomericpoly-electrolytic beads that bind proteins through an empiricallyderived chemistry combining elements of polymer composition,cross-linking architecture and charge properties. As withbio-polymers like DNA and Heparin, governing their reactivity is thespatial presentation of the electrostatic groups along a flexiblepolymer chain.
Unlikeimmuno-affinity, the surfaces utilized are disposable eliminatingcycle to cycle variance and cross-contamination. AlbuSorb™is supplied as a dry powder. Simply weigh, centrifuge and/or filter,and recover the albumin depleted serum in the supernatant.
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