Creative PEGWorks /8-Arm PEG-Acrylate, MW 20k/5g/PSB-822-5g

8-Arm PEG-Acrylate is a multiarm PEG derivative with acrylate groups at each terminal of the eight arms connected to onehexaglycerol core. The 8arm-PEG acrylate can be used for radical initiator or UV light induced polymerization to synthesize PEG hydrogel. 8-Arm PEG-methacrylate is provided through our custom synthesis service. 4-Methoxyphenol or MeHQ at ~ 200 ppm is added as inhibitors.

References: 1. Matthias P. Lutolf et al, Designer matrices for intestinal stem cell and organoid culture, Nature, 2016, 539, 560-564, doi:10.1038/nature20168, Text.

2. PEG Hydrogels - Injectable laminin-functionalized hydrogel for nucleus pulposus regeneration, Biomaterials, 2013 (34): 7381-7388, Text.

3. Improved vascularization of porous scaffolds through growth factor delivery from heparinized polyethylene glycol hydrogels, Acta Biomaterialia, 2017, Text.

4. A tunable hydrogel system for long-term release of cell-secreted cytokines and bioprinted in situ wound cell delivery, J Biomed Mater Res Part B: Appl Biomater, 105B: 1986–2000, 2017, Text.

5. N-cadherin is Key to Expression of the Nucleus Pulposus Cell Phenotype under Selective Substrate Culture Conditions, Scientific Reports 6, Articlenumber:28038 (2016), Text.

6. Combinatorial Screening of Nanoclay Reinforced Hydrogels: A Glimpse of the “Holy Grail” in Orthopedic Stem Cell Therapy? ACS applied materials & interfaces(2018), Text.

7.Bioprinted trachea constructs with patient matched design, mechanical and biological properties, 2019, Biofabrication, 2019, doi: 10.1088/1758-5090/ab5354

8.Verteporfin treatment controls morphology, phenotype, and global gene expression for cells of the human nucleus pulposus, JOR Spine. 2020;e1111, doi: 10.1002/jsp2.1111

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