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Anti Ga13 Rabbit Polyclonal Antibody188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Anti Ga13 Rabbit Polyclonal Antibody
货号：21005
抗体名：抗Ga13兔多克隆抗体
抗体英文名：AntiGa13RabbitPolyclonalAntibody
靶点：Ga13
应用范围：WB,IF
宿主：兔
供应商：NewEastbio
数量：30
级别：实验级
目录编号：21005
抗原来源：兔
保质期：1年
适应物种：脊椎动物
标记物：无
克隆性：是
保存条件：-20℃
形态：液体
免疫原：RecombinantfulllengthGα13protein
规格：100ul
Gα13[21005]
[100µL]		 
 
CatalogNumber:  21005
GeneSymbol:  Ga13
Description:  Anti-Gα13 RabbitPolyclonalAntibody
Background:  HeterotrimericGproteinsareessentialcellularsignaltransducers.Gα13isoneoftheGproteinsthatcouldmediatecellmigrationandangiogenesis.OtherbiochemicalandphysiologicalfunctionsofGα13 arebeingexplored.
Immunogen:  RecombinantfulllengthGα13 protein
Applications:  ELISA,WB,IHC
RecommendedDilutions:  
ELISA1:100-1:5000
WB1:100-1:2000
IHC1:50-1:100
Concentration:  1mg/ml
Host:  Rabbit
Format:  Liquid
Clonality:  Polyclonal
Isotype:  
Purity:  Purifiedfromserum
Storagebuffer:
Preservative:  no
Constituents:  PBS(withoutMg2+ andCa2+),pH7.4,150mMNaCl,50%glycerol
SpeciesReactivity:  Gα13 polyclonalantibodyrecognizesGα13 ofvertebrates.
StorageConditions:  Storeat-20°C.Avoidfreeze/thawcycles
 
Westernblot:  
WesternblotanalysisofGα13 proteins.MEFwhole-celllysateswereusedforwesternblotwithanti-Gα13polyclonalantibody(Cat.#21005).
Immunofluorescence:  
Immunofluorescenceofmouseembryonicfibroblast(MEF)cells.Wild-typeMEFcells(toppanel)andGα13doubleknock-outcells(Gα13 -/-,bottompanel)werefixedandstainedwithanti-Gα13 polyclonalantibody(Cat.#21005).Arrowsindicatethedorsalrufflestrctureofonecell.
Publications:
1.  Resistancetoinhibitorsofcholinesterase-8A(Ric-8A)iscriticalforgrowthfactorreceptor-inducedactincytoskeletalreorganization
    JBiolChem.2011Sep2;286(35):31055-61
2.  AgonistactivationoftheGprotein-coupledreceptorGPR35involvestransmembranedomainIIIandistransducedviaGalphaandbeta-arrestin-2
    BrJPharmacol.2011Feb;162(3):733-48
3.  Gα12/13inhibitionenhancestheanti-cancereffectofbortezomibthroughPSMB5downregulation
    Carcinogenesis(2010)
4.  SuppressionoftumorangiogenesisbyGalpha(13)haploinsufficiency
    JBiolChem.2009Oct2;284(40):27409-15
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