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NFE2L2 Protein V32T mutant

货号:10452
CAS号:10452
供应商:NewEastBio
数量:30000
英文名:NFE2L2ProteinV32Tmutant
保质期:一年
保存条件:-20℃
规格:100μl
NFE2L2ProteinV32Tmutant[10452]
[100ul]
 
CatalogNumber:  10452
ProductName:   NFE2L2ProteinV32Tmutant
Synonyms:  Nuclearfactor(erythroid-derived2)-like2,Nrf2
Source:  Human,recombinantfulllength,His6-tag
ExpressionHost:  E.coli
MolecularWeight:  26kDa
Purity:  >99%bySDS-PAGE
Introduction:  NFE2L2proteinisencodedbyNFE2L2gene.Itisabasicleucinezipperproteinthatregulatestheexpressionofantioxidantproteinsthatprotectagainstoxidativedamagetriggeredbyinjuryandinflammation.SeveraldrugsthatstimulatetheNFE2L2pathwayarebeingstudiedfortreatmentofdiseasesthatarecausedbyoxidativestress.
AminoAcidSequence  (1-170)
MMDLELPPPGLPSQQDMDLIDILWRQDIDLGTSREVFD
FSQRRKEYELEKQKKLEKERQEQLQKEQEKAFFAQLQL
DEETGEFLPIQPAQHIQSETSGSANYSQVAHIPKSDAL
YFDDCMQLLAQTFPFVDDNEVSSATFQSLVPDIPGHIE
SPVFIATNQAQSPETSVA
Properties
PhysicalAppearance(form):  Dissolvedin20mMTris-HCl,pH8.0,150mMNaCl.
PhysicalAppearance(form):  Whiteorclear
Concentration:  1mg/mL
Storage:   -80°C
PreparationInstructions:  
Addingof10mMβ-mercaptoethanolor1mMDTTintothesolutiontoprotecttheproteinisrecommendedandusingofnon-ionicdetergentssuchasn-Dodecylβ-D-maltoside(DoDM)orpolyethylenedetergents(e.g.C12E10)alsohelptostabilizetheprotein.Avoidrepeatedfreezingandthawing.

ThepurityofHis-taggedNFE2L2V32TwasdeterminedbySDS-PAGEandCoomassieBrilliantBlueStaining.

References:  
1.MoiPetal.,Proc.Natl.Acad.Sci.U.S.A.91(21):9926-30. 
2.GoldRetal.,N.Engl.J.Med.367(12):1098-107.
Datasheet:  
 

 

温馨提示:不可用于临床治疗。

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