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Rab7 Protein188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Rab7 Protein

货号:10167
CAS号:10167
供应商:NewEastBio
数量:3000
英文名:Rab7Protein
保质期:一年
保存条件:-20℃
规格:100μl
Rab7Protein[10167]
[100µg]
 
CatalogNumber:  10167
ProductName:  Rab7Protein
Synonyms:  MemberRASoncogenefamily,Rab7a,MGC102153
Source:  Human,recombinantfulllength,His6-tag
ExpressionHost:  E.coli
MolecularWeight:  23kDa
Purity:  >95%bySDS-PAGE
Introduction:  MembersoftheRabfamilyofRas-relatedGTP-bindingproteinsareimportantregulatorsofvesiculartransportandarelocatedinspecificintracellularcompartments.Rab7hasbeenlocalizedtolateendosomesandshowntobeimportantinthelateendocyticpathway.Inaddition,ithasbeenshowntohaveafundamentalroleinthecellularvacuolationinducedbythecytotoxinVacAofHelicobacterpylori.
AminoAcidSequence  (1-207)
MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQ 
ERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQV 
ATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKASAESCSC
Properties
PhysicalAppearance(form):  Dissolvedin20mMTris-HCl,pH8.0,150mMNaCl.
PhysicalAppearance(form):  Whiteorclear
Concentration:  1mg/mL
Storage:   -80°C
PreparationInstructions:  
Centrifugethevialbeforeopenthecapandreconstituteinwater.Addingof10mMβ-mercaptoethanolor1mMDTTintothesolutiontoprotecttheproteinisrecommendedandusingofnon-ionicdetergentssuchasn-Dodecylβ-D-maltoside(DoDM)orpolyethylenedetergents(e.g.C12E10)alsohelptostABIlizetheprotein.Avoidrepeatedfreezingandthawingafterreconstitution.ThepurityofHis-taggedRab7wasdeterminedbySDS-PAGEandCoomassieBrilliantBlueStaining.
References:  
1.Edinger,A.L.etal.,Dev.Cell5:571-582,2003.2.Houlden,H.etal.,Ann.Neurol.56:586-590,2004. 
3.Meggouh,F.etal.,Neurology67:1476-1478,2006. 
4.Rak,A.etal.,Cell117:749-760,2004. 
5.Verhoeven,K.etal.,Am.J.Hum.Genet.72:722-727,2003.
Datasheet:  

 

温馨提示:不可用于临床治疗。

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