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AntiRheB Mouse Monoclonal Antibody188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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AntiRheB Mouse Monoclonal Antibody
货号：26015
抗体名：RheB
抗体英文名：RheBAntibody
靶点：RheB
浓度：1mg/ml
应用范围：ELISA、WB、IHC
宿主：Mouse
供应商：NewEastBio
数量：30000
级别：实验级
目录编号：26015
抗原来源：Mouse
保质期：两年
适应物种：脊椎动物
标记物：FITC
克隆性：是
保存条件：-20°C
形态：液体
亚型：IgG
免疫原：Mouse
规格：100μl
RheB[26015]
[100µL]		 
 
CatalogNumber:  26015
GeneSymbol:  RHEB
Description:  Anti-RheBMouseMonoclonalAntibody
Background:  RheB(RasHomologEnrichedinBrain)isanevolutionarilyconservedmemberoftheRas-familyofsmallGTP-bindingproteinsoriginallyfoundtoberapidlyinducedbysynapticactivityinthehippocampusfollowingseizure.Whileitisexpressedatrelativelyhighlevelsinthebrain,RheBiswidelyexpressedinothertissuesandmaybeinducedbygrowthfactorstimulation.RheBhasanimportantroleinregulatingtheinsulin/TORsignalingpathway.Themammaliantargetofrapamycin,mTOR,isaserine/threonineproteinkinasethatactsasasensorforATPandaminoacids,balancingtheavailABIlityofnutrientswithtranslationandcellgrowth.Thetuberin/hamartin(TSC2/TSC1)complexinhibitsmTORactivityindirectlybyinhibitingRheBviatuberinsGAPactivity.
Immunogen:  RecombinantfulllengthproteinofRheB.
Applications:  ELISA,WB,IHC
RecommendedDilutions:  
ELISA:1:100-1:5000 
WB:1:100-1:2000 
IHC:1:50-1:100
Concentration:  1mg/ml
Host:  mouse
Format:  Liquid
Clonality:  Monoclonal
Isotype:  IgG
Purity:  Purifiedfromascites
Storagebuffer:
Preservative:  no
Constituents:  PBS(withoutMg2+ andCa2+),pH7.4,150mMNaCl,50%glycerol
SpeciesReactivity:  RheBantibodyrecognizesRheBproteinsofvertebrates.
StorageConditions:  Storeat-20°C.Avoidfreeze/thawcycles
Westernblot:  
WesternblotanalysisofRheBproteins.HEK-293whole-celllysatewasusedforWesternblot.
Publications:
1.  InducIBLeNitricOxideSynthaseDrivesmTORPathwayActivationandProliferationofHumanMelanomabyReversibleNitrosylationofTSC2
    CancerRes.2014Feb15;74(4):1067-78
2.  SynGAPRegulatesProteinSynthesisandHomeostaticSynapticPlasticityinDevelopingCorticalNetworks
    PLoSOne.2013Dec31;8(12):e83941
温馨提示：不可用于临床治疗。

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