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AntiCTNNB1(T41A) Mouse Monoclonal Antibody188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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AntiCTNNB1(T41A) Mouse Monoclonal Antibody
货号：26305
抗体名：CTNNB1(T41A)抗体
抗体英文名：CTNNB1(T41A)antibody
靶点：Beta-catenin,CTNNB,Cateninbeta-1
浓度：1mg/ml
应用范围：ELISA,WB,IHC
宿主：Mouse
供应商：NewEastBio
数量：30000
级别：实验级
目录编号：26305
抗原来源：Mouse
保质期：两年
适应物种：脊椎动物
标记物：FITC
克隆性：是
保存条件：-20℃
形态：液体
亚型：IgG
免疫原：AsyntheticpeptidefromtheinternalregionofCTNNB1whichincludesthemutationofT41A,humanorigin.
规格：100μl
CTNNB1(T41A)[26305]
[100ul]		 
CatalogNumber:  26305
GeneSymbol:  Beta-catenin,CTNNB,Cateninbeta-1
Description:  Anti-CTNNB1(T41A)MouseMonoclonalAntibody
Background:  CTNNB1proteinisadualfunctionprotein.Itisasubunitofacomplexofproteinsthatfromadherensjunctions,whichareimportantfortheestablishmentandmaintenanceofepithelialcelllayersbyregulatingcellgrowthandadhesionbetweenadjacentcells.CTNNB1proteinalsopullsdoubledutyasanintracellularsignaltransducerintheWntsignalingpathway.MutationsofCTNNB1havebeenimplicatedinthepathogenesisofseveralcancers.
Immunogen:  AsyntheticpeptidefromtheinternalregionofCTNNB1whichincludesthemutationofT41A,humanorigin.
Applications:  ELISA,WB,IHC
RecommendedDilutions:  
ELISA:1:1000-1:5000 
WB:1:500-1:2000 
IHC:1:50-1:100
Concentration:  1mg/ml
Host:  Mouse
Format:  Liquid
Clonality:  Monoclonal
Isotype:  
Purity:  Purifiedfromascites
Storagebuffer:
Preservative:  no
Constituents:  PBS(withoutMg2+ andCa2+),pH7.4,150mMNaCl,50%glycerol
SpeciesReactivity:  RecognizesT41Amutant,butnotwild-typeCTNNB1ofvertebrates.
StorageConditions:   Storeat-20°C.Avoidfreeze/thawcycles
 
Westernblot:  
WesternblotanalysisofrecombinantCTNNB1(T41A)andwildtypeproteins.PurifiedHis-taggedCTNNB1(T41A)protein(lane2)andcorrespondingwild-typeprotein(lane1)wereblottedwithanti-CTNNB1(T41A)monoclonalantibody(Cat.#26305).
Immunofluorescence:  
ImmunofluorescenceofcellsexpressingCTNNB1proteinswithanti-CTNNB1(T41A)antibody.HEK293TcellsweretransfectedwithpCDNA3-GFP-CTNNB1(WT)plasmid(leftcolumn)orpCDNA3-GFP-CTNNB1(T41A)plasmid(rightcolumn),thenfixedandstainedwithanti-CTNNB1(T41A)monoclonalantibody(Cat.#26305).

 

温馨提示：不可用于临床治疗。

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