Details
Thepeptidehormoneosteocalcinisinvolvednotonlyinboneformation,italsoplaysanimportantroleinglucosemetabolismandcouldregulatetestosteron.Inmice,onlythecompletelydecarboxylatedformofthepeptideshowsthelatterhormonalactivities,whereasinhumans,osteocalcin,partiallydecarboxylatedosteocalcins,andtheuncarboxylatedpeptideseemtobeinvolved.Generally,obeseindividualshavebeenshowntohavelowerosteocalcin(s)levelsthannon-obesecontrols,andtype2diabeticindividualshavelowerplasmaosteocalcinthannon-diabeticindividuals.
ItemNumber4063516
OneLetterCodeYLYQWLGAPVPYPDPLEPRREVCELNPDCDELADHIGFQEAYRRFYGPV
SynonymsOsteocalcin(1-49)(human)(decarboxylated)
MolecularFormulaC₂₆₆H₃₈₁N₆₇O₇₆S₂
RelativeMolecularMass5797.49
CASRegistryNumber[1927927-11-4]net
SourceSynthetic
StorageConditions-20±5°C
KeywordsBonehormoneinvolvedinglucosemetabolism
AreasofInterestDiabetes
ObesityResearch
Productcitations
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