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| Cat.No. : | Kit-0890 |
| Product Overview : | The Wnt/β-catenin signaling pathway controls a large and diverse set of cell fate decisions in embryonic development, adult organ maintenance and disease. Wnt proteins bind to receptors on the cell surface, initiating a signaling cascade that leads to stabilization and nuclear translocation of β-catenin. β-catenin then binds to TCF/LEF transcription factors in the nucleus, leading to transcription and expression of Wnt-responsive genes. |
| Applications : | • Monitor Wnt /β-catenin signaling pathway activity.• Screen for activators or inhibitors of the Wnt /β-catenin signaling pathway.• Study effects of RNAi or gene overexpression on the activity of the Wnt /β-catenin pathway. |
| Storage : | Stable at least 12 months from date of receipt, when stored as directed (-20°C). |
| Size : | 500 reactions |
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