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Human insulin-like growth factor-I (IGF-I) is a single chain 70 amino acid polypeptide that shares structural homology with insulin and human IGF-II. IGF-I plays a critical role in growth, differentiation and development via autocrine, paracrine and endocrine mechanisms. It is a mitogen and also has effects on cell migration and differentiation. IGF-I binds to the type I IGF receptor and most of its actions are probably mediated through inducing signal transduction via this receptor. IGF-I also binds to each of the six IGF binding proteins (IGFBPs). This binding also regulates the biological function of IGF-I. IGF-I is highly conserved across species which suggests an important role for the peptide. Human IGF-I is present in high concentrations in normal adult human serum in a complex with IGFBP-3 and the acid-labile subunit (ALS) and mediates many of the actions of Growth Hormone. IGF-I is a regulator of metabolism and is also implicated in the pathophysiology of cancer, diabetes and obesity.
Media grade human IGF-I is a high quality reagent at an economical cost to enable studies where higher quantities of peptide are required.
IGF-I (Media Grade) specifications
IGF-I SDS
matriks/Shikari® (S-ATP) Anti-Pembrolizumab ELISA w/confirmation/PEM-QNS-KEY
intactgenomics/Methionine Auxotrophic LBA4404 | ig® | Intact Genomics/15x50μl/1076-15
goprolytix/Proteolytic Activation of Prothrombin/1 mg, 200 µg/BCT-DFP
novateinbio/Dynorphin A ( 13-17 ) Porcine Peptide/5mg/PE-54024_5mg
matriks/Shikari® (Q-ETA) Etanercept ELISA/ETA-FD-ENB
intactgenomics/Agrobacterium ElectroComponent Combo Pack | Intact Genomics/12x50µl/1290-24
Jackson/Peroxidase AffiniPure Goat Anti-Mouse IgG (H+L)/2.0 ml/115-035-003
Jackson/Peroxidase AffiniPure Goat Anti-Rabbit IgG (H+L)/2.0 ml/111-035-003
Qubit™ dsDNA BR Assay Kit Q32853现货
Invitrogen Q32855 Qubit™ RNA HS Assay Kit现货促销
LUCK-1G,D-Luciferin, Potassium Salt 钾盐现货
GoldBio/D-Luciferin, Sodium Salt (Proven and Published™)/LUCNA-1G/1 g