DCDAPH(1,1-dicyano-6-(4-N,N-dimethylaminophenyl)-1,3,5-hexatriene)isaNIRfluorescentprobethathasprovedtohaveaffinitytoAβplaquesinfluorescentstainingofbrainsectionsaswellasinaninvivobindingassayusingAβ1-42aggregates1. DCDAPHhashighaffinity(Ki=37nM,Kd=27nM)toAβ1-42aggregates.
1.J.Am.Chem.Soc.dx.doi.org/10.1021/ja4052922