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Biotium/DiBAC4(3)/61011/25-mg

DiBAC4(3)(Bis-(1,3-Dibarbituricacid)-trimethineoxanol)isaso-calledtranslationalmembranepotentialdyethatredistributeswithinthecellmembranewhenmembranepotentialchanges(1,2).Thefluorescenceofthedyeisenhancedwhenthedyeentersthecellmembraneasaresultofmembranedepolarization.

DiBAC4(3)(Bis-(1,3-Dibarbituricacid)-trimethineoxanol)isaso-calledtranslationalmembranepotentialdyethatredistributeswithinthecellmembranewhenmembranepotentialchanges(1,2).Thefluorescenceofthedyeisenhancedwhenthedyeentersthecellmembraneasaresultofmembranedepolarization.Therateoffluorescenceresponseofthedyetomembranepotentialchangeisusuallyslowerthanthatofthestyryldyedi-4-ANEPPS,butthefluorescencesignalchangefortheformerissignificantlylargerthanforthelatterdye.DiBAC4(3)hasapplicationsinhigh-throughputdrugscreening.

  • OrangesolidsolubleinDMSOorDMF
  • Storeat-20°Candprotectfromlight
  • C27H40N4O6
  • MW:519
  • [70363-83-6]

References

1.ChemPhysLipids69,137(1994).

2.BiochimBiophysActa771,208(1984).

3.JBiomolScreening1(2),75(1996).

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