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Biotium/DiI/60010/50mg

DiIisawidelyusedcarbocyaninemembranedyethatlabelscellmembranesbyinsertingitstwolong(C18carbon)hydrocarbonchainsintothelipidbilayer.Particularly,ithasbeenextensivelyusedfortheanterogradeandretrogradelabelingofneurons.

DiIC18(3);1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine

DiIisawidelyusedcarbocyaninemembranedyethatlabelscellmembranesbyinsertingitstwolong(C18carbon)hydrocarbonchainsintothelipidbilayer.Particularly,ithasbeenextensivelyusedfortheanterogradeandretrogradelabelingofneurons.Theintensefluorescenceandhighphotostabilityofthedyemakeitpossibletovisualizethefinestructures(axonsanddendrites)oftheneurons.Duetoitslowtoxicityandthetendencytogivehighlystablecelllabeling,thedyehasalsobeengenerallyusedforlongtermcelltracingofcellsbothinculturesandinlivingembryosoranimals.Pleasealsoseeourready-to-useCellBrite™CellMembraneLabelingSolutions.

  • λExEm(MeOH)=549/565nm
  • ε=148,000
  • Darkredsolidsolubleinethanol,DMForDMSO
  • Storeat-20°C
  • C59H97ClN2O4
  • MW:933.88
  • [41085-99-8]

References

1.Biochemistry19,6050(1980).

2.J.

Immunology127,893(1981).

3.Trends

inNeurosci9,333(1989).

4.JCellBiol103,171(1986).


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