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Bis-sulfone-PEG4-Tetrazineenablessite-specificincorporationofatetrazinemoietyontoantibodiestoformwelldefinedconjugates.Unlikeconjugatespreparedthroughconventional,maleimide-basedlabelingchemistrythatleavesdisulfidebridgesin“openform”andproducesaheterogeneousmixturelabeledspecieswithDAR1-8,conjugatespreparedwithbis-sulfonereagentsbenefitsfromreducedheterogeneityandenhancedstability.
Learnmoreaboutbis-sulfonereagentsandtwo-steplabelingapproach.
| Molecularweight | 883.04 |
| Chemicalcomposition | C42H54N6O11S2 |
| CAS | N/A |
| Solubility | DMSO,DMF,DCM,THF,Chloroform |
| Purity | >90%(HPLC) |
| Appearance | Redamorphoussolidtoredoil |
| StorageConditions | -20C |
| Shippingconditions | Ambienttemperature |