Extraordinarystrengthofthestreptavidin-biotininteractionallowsforefficientcapturingofevenhighlydilutetargets;however,itmakesrecoveryofproteinsfromaffinityresinschallenging.DdeBiotin-Alkyneprobeeliminatesamajorlimitationofthestreptavidin-biotinaffinitypurification.ThisreagentcontainsabiotinmoietylinkedtoanalkynemoietythroughaspacerarmcontainingaDdelinker.Capturedbiomoleculescanbeefficientlyreleased,typically>90%.

| Molecularweight | 650.83 |
| Molecularweightleftbehind | 55.07 |
| Chemicalcomposition | C32H50N4O8S |
| CAS | N/A |
| Solubility | DMSO,DMF,THF,DCM,Chloroform |
| Purity | >95%(HPLC) |
| Appearance | Glass-likesolid |
| Storageconditions | -20C |
| Shippingconditions | Ambienttemperature |