TopotecanisananticancerchemotherapeuticcompoundthatinhibitstopoisomeraseIandisclinicallyusedtotreatvariouscancers.Topotecaninducesapoptosisinretinocytomacellsandovariancancercells.
| CasNo. | 119413-54-6 |
|---|---|
| Purity | ≥98% |
| Formula | C23H25N3O5•HCl |
| FormulaWt. | 457.91 |
| ChemicalName | (4S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3,4:6,7]indolizino[1,2-b]-quinoline-3,14(4H,12H)-dionehydrochloride |
| Synonym | Hycamtin;NSC-609669;SKF-104864A |
| MeltingPoint | 213-218°C(dec.) |
| Solubility | Solubleinmethanol,water(92mg/mlat25°C),DMSO(92mg/mlat25°C),ethanol(<1 mg/ml="" at="" 25="" °c),="" and="" 1:="" 1="" solution="" of="" dmso:="" pbs="" (ph="" 7.2,="" ~0.5=""> |
| Appearance | PaleYellowCrystalPowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | T5761MSDSPDF |
|---|---|
| InfoSheet | T5761InfoSheetPDF |
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