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Adipogen/Canertinib/SYN1030M001/1 mg188bio精品生物—专注于实验室精品爆款的电商平台 - 蚂蚁淘旗下精选188款生物医学科研用品
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Adipogen/Canertinib/SYN1030M001/1 mg
MoreInformation
ProductDetails
SynonymsCI1033;PD-183805
ProductTypeChemical
Properties
FormulaC24H25ClFN5O3
MW486.0
CAS267243-28-7
PurityChemicals≥95%
AppearanceSolid.
SolubilitySolubleinDMSOorethanol.
DeclarationManufacturedbySynKinase.
OtherProductDataTarget:EGFR|KinaseGroup:RTK|Substrate:Tyrosine

ClickhereforOriginalManufacturerProductDatasheet
Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet.
InChiKeyOMZCMEYTWSXEPZ-UHFFFAOYSA-N
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
Use/StabilityStableforatleast2yearsafterreceiptwhenstoredat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
Canertinibisanorallybio-availableEGFRinhibitorwithpotentialanti-neoplasticandradio-sensitizingactivities.IthasIC(50)valuesof1.5nMand9.0nMagainstEGFRandErbB2respectively,withnoactivityagainstPDGFR,FGFR,InsR,PKC,orCDK1/2/4.
ProductReferences
  1. TheHERtyrosinekinaseinhibitorCI1033enhancescytotoxicityof7-ethyl-10-hydroxycamptothecinandtopotecanbyinhibitingbreastcancerresistanceprotein-mediateddrugefflux:C.Erlichman,etal.;CancerRes.61,739(2001)

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