Potent and competitive NMDA receptor antagonist. Binds at the glutamate site.
Shows some selectivity (~7-10-fold) for GluN1/2A (NR1/2A) over GluN1/2B (NR1/2B) subunit containing receptors (IC50 values are 31 and 215 nM at GluN1/2A and GluN1/2B respectively).
Shows anticonvulsant activity. Active in vivo.

![PEAQX [459836-30-7] PEAQX [459836-30-7]](https://www.ebiomall.com/images/hellobio/201710/hb2841.png)