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Hello Bio/Zonisamide/HB0675/

Productoverview

  • Name
    Zonisamide
  • Shortdescription
    Non-selectiveNa+/Ca2+channelblocker
  • BIOLOGicaldescription
    Non-selectivevoltage-dependentNa+andT-typeCa2+channelblocker.EnhancesBK(Ca)channelsbyincreasingthetimetheyareopen.ScavengesfreerADIcalsandinfluencesmonoamine,glutamateandGABAneurotransmission.Actsasananti-epilepticandshowsneuroprotectiveandsomeanti-Parkinsonianactions.
  • Biologicalaction
    Blocker
  • Purity
    >99%
  • Ourproductsinaction
    SubmitYourCitationNow

Properties

  • Chemicalname
    1,2-Benzisoxazole-3-methanesulfonamide
  • MolecularWeight
    212.22
  • Chemicalstructure
    Zonisamide [68291-97-4]
  • MolecularFormula
    C8H8N2O3S
  • CASNumber
    68291-97-4

StoringandUsingYourProduct

  • Storageinstructions
    +4°C
  • Solubilityoverview
    solubleinwater(10mM)orDMSO(100mM)
  • Important
    ThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.

ReferencesforZonisamide

  • Zonisamide:anewantiepilepticdrug.

    SobieszekGetal(2003)PolJPharmacol55(5):683-9.
    PubMedID:14704463

  • Activationbyzonisamide,anewerantiepilepticdrug,oflarge-conductancecalcium-activatedpotassiumchannelindifferentiatedhippocampalneuron-derivedH19-7cells.

    HuangCWetal(2007)JPharmacolExpTher321(1):98-106.
    PubMedID:17255467

  • Zonisamideattenuatesα-synucleinneurotoxicitybyanaggregation-independentmechanisminaratmodeloffamilialParkinson"sdisease.

    ArawakaSetal(2014)PLoSOne9(2):e89076.
    PubMedID:24586512
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